Surge in Flu Cases Linked to H3N2 Subclade K in San Diego

Hospital scene showing staff dealing with a surge in flu cases due to H3N2 subclade K strain.

San Diego, February 4, 2026

San Diego County is facing a significant rise in flu cases attributed to the H3N2 subclade K strain. This mutated variant of the seasonal flu virus has led to increased hospitalizations and flu-related deaths. Health officials advise residents to take preventive measures, including vaccination and practicing good hygiene. The situation is being monitored closely as the subclade K strain displays aggressive characteristics, raising concerns about public health.

San Diego, CA – Surge in Flu Cases Linked to Subclade K Strain

San Diego County is experiencing a significant increase in influenza cases, primarily attributed to the H3N2 subclade K strain, a mutated variant of the seasonal flu virus. This surge has led to a notable rise in hospitalizations and flu-related deaths across the region.

Current Situation in San Diego County

As of early February 2026, San Diego County has reported a substantial uptick in flu cases, with hospitalizations reaching levels not seen in previous seasons. The H3N2 subclade K strain has been identified as the predominant cause of this increase. Health officials are closely monitoring the situation and have urged residents to take preventive measures.

Characteristics of the H3N2 Subclade K Strain

The H3N2 subclade K strain is a mutated version of the seasonal influenza A virus. This variant has been associated with more severe symptoms and a higher rate of hospitalizations compared to other strains. Symptoms commonly include fever, body aches, cough, and fatigue. The mutation has raised concerns about the effectiveness of the current flu vaccine, as it may not fully protect against this strain. However, health authorities emphasize that vaccination remains a crucial tool in reducing the severity of illness and preventing complications.

Preventive Measures and Recommendations

Health experts recommend the following steps to mitigate the impact of the flu season:

  • Vaccination: Residents are encouraged to receive the flu vaccine if they have not already done so. While the vaccine may not offer complete protection against the subclade K strain, it can still reduce the severity of illness and prevent hospitalizations.
  • Hygiene Practices: Regular handwashing with soap and water, covering coughs and sneezes, and avoiding close contact with sick individuals can help prevent the spread of the virus.
  • Staying Home When Sick: Individuals exhibiting flu-like symptoms should stay home to prevent transmitting the virus to others.

Background on the H3N2 Subclade K Strain

The H3N2 subclade K strain emerged in mid-2025 and has since spread to various regions, including the United States. Its rapid transmission and increased severity have led to heightened concerns among public health officials. The mutation in this strain has resulted in changes that may affect the immune system’s ability to recognize and combat the virus, making it more challenging to control its spread.

Impact on Hospitalizations and Mortality

Nationwide, the flu season has been particularly severe, with hospitalizations and deaths surpassing previous records. In San Diego County, the number of flu-related deaths has already exceeded the combined total of the last two seasons. Health officials attribute this increase to the aggressive nature of the subclade K strain and the challenges it poses to existing immunity levels within the community.

Conclusion

The emergence of the H3N2 subclade K strain has significantly impacted San Diego County, leading to a surge in flu cases, hospitalizations, and deaths. Residents are urged to take preventive measures, including vaccination and good hygiene practices, to help control the spread of this variant and protect vulnerable populations.

Frequently Asked Questions (FAQ)

What is the H3N2 subclade K strain?

The H3N2 subclade K strain is a mutated variant of the seasonal influenza A virus, associated with more severe symptoms and higher hospitalization rates compared to other strains.

How does the subclade K strain affect the flu vaccine’s effectiveness?

The mutation in the subclade K strain may reduce the flu vaccine’s effectiveness against this variant. However, vaccination remains important as it can still lessen the severity of illness and prevent hospitalizations.

What preventive measures are recommended to combat the flu surge?

Health experts recommend vaccination, regular handwashing, covering coughs and sneezes, avoiding close contact with sick individuals, and staying home when exhibiting flu-like symptoms.

How has the subclade K strain impacted hospitalizations and deaths in San Diego County?

In San Diego County, flu-related deaths have already exceeded the combined total of the last two seasons, with hospitalizations reaching levels not seen in previous years. This increase is attributed to the aggressive nature of the subclade K strain.

What is the current flu situation in San Diego County?

As of early February 2026, San Diego County is experiencing a significant increase in flu cases, primarily due to the H3N2 subclade K strain. Hospitalizations and flu-related deaths have risen notably, prompting health officials to monitor the situation closely and advise residents on preventive measures.

Key Features of the H3N2 Subclade K Flu Strain Surge in San Diego County

Feature Details
Strain Identified H3N2 subclade K
Impact on Hospitalizations Significant increase in flu-related hospitalizations
Impact on Mortality Flu-related deaths have exceeded the combined total of the last two seasons
Vaccine Effectiveness Current flu vaccine may not fully protect against this strain, but still offers some protection
Preventive Measures Vaccination, good hygiene practices, and staying home when sick are recommended

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Author: STAFF HERE SAN DIEGO WRITER

The SAN DIEGO STAFF WRITER represents the experienced team at HERESanDiego.com, your go-to source for actionable local news and information in San Diego, San Diego County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as Comic-Con International, San Diego County Fair, and San Diego Pride Festival. Our coverage extends to key organizations like the San Diego Regional Chamber of Commerce and United Way of San Diego County, plus leading businesses in biotechnology, healthcare, and technology that power the local economy such as Qualcomm, Illumina, and Scripps Health. As part of the broader HERE network, including HEREAnaheim.com, HEREBeverlyHills.com, HERECostaMesa.com, HERECoronado.com, HEREHollywood.com, HEREHuntingtonBeach.com, HERELongBeach.com, HERELosAngeles.com, HEREMissionViejo.com, and HERESantaAna.com, we provide comprehensive, credible insights into California's dynamic landscape.

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