Commercial Fire Breaks Out in Downtown San Diego

Firefighters battling a blaze at a vacant commercial building in San Diego

San Diego, December 23, 2025

A commercial fire erupted early Monday morning in a vacant building at 1323 Sixth Avenue in San Diego’s Cortez Hill neighborhood. The San Diego Fire-Rescue Department responded swiftly with over 100 personnel, bringing the flames under control within an hour. Fortunately, no injuries were reported, but the cause of the fire is still under investigation. Witnesses noted individuals exiting the building during the blaze, prompting road closures as firefighters managed the scene and searched for lingering hot spots. Recent trends of fires in empty buildings raise safety concerns in the community.


San Diego, CA – Early Monday morning, a commercial fire broke out in a vacant building located at 1323 Sixth Avenue in downtown San Diego’s Cortez Hill neighborhood. The San Diego Fire-Rescue Department (SDFD) received the emergency call at approximately 4:10 a.m., quickly mobilizing over 100 personnel to combat the flames. Firefighters accessed the second floor using ladders and fought the blaze across stairwells and lower levels, bringing it under control within an hour. Fortunately, no injuries were reported, and the cause of the fire remains under investigation.

While the building was deemed “abandoned,” witnesses reported seeing individuals exit the structure during the fire. Road closures followed as firefighters assessed the damage and continued checking for any remaining hot spots. Assistance was provided by personnel from the National City and Coronado fire departments.

### Firefighting Response
The SDFD’s swift response included the deployment of six trucks, four medics, and 13 engines, showcasing the commitment and efficiency of local emergency services. Their efforts minimized potential dangers in a downtown area that is increasingly adapting to a growing population and tourist influx.

### Road Closures
To facilitate firefighting operations and ensure public safety, multiple road closures were enacted around the area. Local drivers were advised to seek alternate routes while crews worked diligently to address the situation.

### Assistance from Neighboring Departments
The collaboration between local firefighting units, including those from National City and Coronado, underscores the effective regional partnerships that enhance public safety responses during emergencies. Such teamwork is essential for addressing larger-scale incidents, particularly as urban regions like San Diego continue to expand.

### Background
Recent months have seen a troubling trend of fires in abandoned buildings throughout San Diego. Notably, on December 25, 2024, a devastating fire at the former InCahoots Dance Hall & Saloon in Mission Valley led to an arrest for arson in connection with that incident. This calls into scrutiny the safety measures and regulations regarding vacant structures in the community.

### Fire Safety Tips
In light of these incidents, residents are encouraged to stay informed about fire safety measures. Reporting any suspicious activities can serve as a preventative measure against future occurrences, enhancing community awareness and vigilance.

### FAQ

What caused the fire at 1323 Sixth Avenue?

The cause of the fire remains under investigation.

Were there any injuries reported?

No injuries were reported during the incident.

How many personnel responded to the fire?

Over 100 personnel from the San Diego Fire-Rescue Department responded to the scene.

Have there been similar incidents in San Diego recently?

Yes, there have been several fires in abandoned buildings in San Diego in recent months.

What should residents do to stay safe?

Residents are encouraged to stay informed about fire safety measures and report any suspicious activity to local authorities to help prevent future incidents.

### Key Features

Feature Details
Location 1323 Sixth Avenue, Cortez Hill neighborhood, San Diego, CA
Time of Incident Approximately 4:10 a.m., December 22, 2025
Firefighting Response Over 100 personnel, including six trucks, four medics, and 13 engines
Cause of Fire Under investigation
Injuries No injuries reported
Assisting Departments National City and Coronado Fire Departments
Recent Similar Incidents Fire at former InCahoots Dance Hall & Saloon on December 25, 2024

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Author: STAFF HERE SAN DIEGO WRITER

The SAN DIEGO STAFF WRITER represents the experienced team at HERESanDiego.com, your go-to source for actionable local news and information in San Diego, San Diego County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as Comic-Con International, San Diego County Fair, and San Diego Pride Festival. Our coverage extends to key organizations like the San Diego Regional Chamber of Commerce and United Way of San Diego County, plus leading businesses in biotechnology, healthcare, and technology that power the local economy such as Qualcomm, Illumina, and Scripps Health. As part of the broader HERE network, including HEREAnaheim.com, HEREBeverlyHills.com, HERECostaMesa.com, HERECoronado.com, HEREHollywood.com, HEREHuntingtonBeach.com, HERELongBeach.com, HERELosAngeles.com, HEREMissionViejo.com, and HERESantaAna.com, we provide comprehensive, credible insights into California's dynamic landscape.

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